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September 17, 2015 By Mark Terry, Bio Breaking News Staff The British Medical Journal (BMJ) published an article yesterday that reanalyzed clinical trial data from then Smith Kline Beecham’s Study 329, published in 2001.

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In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This sheet talks about whether exposure to paroxetine may increase the risk for birth defects over that background risk.

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Drugmaker Glaxo Smith Kline is criticized for delaying access to data about its antidepressant paroxetine (Seroxat, Paxil) that would have shown earlier that it is neither safe or effective in adolescents By Kate Kelland LONDON (Reuters) - A medical journal criticised British drugmaker Glaxo Smith Kline on Thursday for delaying access to key data from a trial of its antidepressant paroxetine (Seroxat, Paxil) that would have shown earlier that it is neither safe or effective in adolescents.

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The widely prescribed antidepressant paroxetine -- sold under the names Paxil, Aropax and Seroxat -- has been found to be neither a safe nor effective treatment for depression in adolescents, according a new reanalysis of research orinally published in 2001. It contradicts the findings of the orinal study, which was funded by the drug's manufacturer and concluded that paroxetine was safe and effective in treating major depression in children and teens.


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